Studies on Synthetic Analgesics. XIV
نویسندگان
چکیده
منابع مشابه
Animal experimentation in studying addiction to the newer synthetic analgesics.
HE term addiction, when applied to the syndrome resulting from T the prolonged use of morphine and its congeners in man, by coinmon usage involves three principal components, psychic dependence, physical dependence, and acquired toleranee. In view of the fact that the newer synthetic analgesics produce pharmacological effects, many of which are qualitatively similar to those of morphine and its...
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Recent introduction of new analgesics into the clinic is best described as a slow process with activity classified into two main areas: improving analgesic efficacy/potency and reducing side-effect profile. This review article describes some of the recent advances with an emphasis on use in the acute setting. In this respect, opioids continue to be the mainstay (but not the only) analgesic and ...
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Leupeptins, fermentation products of various strains of Actinomycetes^ showed strong antiplasmin activity2) and were identified as being a mixture of two major components, leupeptin Ac-LL (acetyl-L-leucyl-L-leucyl-DL-argininal, 1) and leupeptin Pr-LL (propionyl-L-leucyl-L-leucyl-DL-argininal, 2), and their analogs containing isoleucine or valine in place of one or two leucine residues of 1 or 2...
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In this study the effect of sintering process in different temperatures on microstructure and morphological properties of sintered hydroxyapatite (HAp) was investigated. HAp powder was prepared by wet precipitation method from following reagents: Ca(OH)2 + H3PO4 in an alkaline conditions. Thermal analysis (TA), X-Ray diffraction method (XRD), FT-IR spectrometry (FT-IR) and scanning electron mic...
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Degradation of clofarabine (3) in 0.9% saline solution at 100 degrees C afforded three degradation products which were determined to be formamidopyrimidines 4-6. Compounds 4 and 5 were assigned as C(1') anomers on the basis of one-dimensional and two-dimensional NMR experiments, whereas 6 was found to be the formamidopyrimidine lacking the sugar moiety. An improved procedure for the synthesis o...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1961
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.81.3_423